Development Processes: NGOs, SHGs & Stakeholders

The 2025 Nobel Prize in Physiology or Medicine has been awarded to Japanese scientist Shimon Sakaguchi and American scientists Mary E. Brunkow and Frederick J. Ramsdell for their pioneering discoveries on regulatory T cells. These cells act as essential "security guards" in the immune system, ensuring it fights off harmful invaders like viruses and bacteria without mistakenly attacking the body's own healthy cells. This breakthrough, announced by the Nobel Committee, highlights the mechanism of peripheral immune tolerance and opens new pathways for treating autoimmune diseases and enhancing cancer therapies, addressing a long-standing puzzle in immunology.